BDBM50240382 1,4-Dihydroxyanthrachinon::1,4-dihydroxy-9,10-anthraquinone::1,4-dihydroxyanthra-9,10-quinone::1,4-dihydroxyanthracene-9,10-dione::1,4-dihydroxyanthraquinone::CHEMBL17594::Chinizarin::quinizarin::quinizarine

SMILES Oc1ccc(O)c2C(=O)c3ccccc3C(=O)c12

InChI Key InChIKey=GUEIZVNYDFNHJU-UHFFFAOYSA-N

Data  1 KI  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50240382   

TargetCasein kinase I isoform delta(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50240382(1,4-dihydroxyanthracene-9,10-dione | quinizarin | ...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CK1deltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50240382(1,4-dihydroxyanthracene-9,10-dione | quinizarin | ...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CK1gamma1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50240382(1,4-dihydroxyanthracene-9,10-dione | quinizarin | ...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CK1alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Rat)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50240382(1,4-dihydroxyanthracene-9,10-dione | quinizarin | ...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of rat liver cytosolic TrxR1 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetThioredoxin reductase 2, mitochondrial(Rat)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50240382(1,4-dihydroxyanthracene-9,10-dione | quinizarin | ...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of rat liver mitochondrial TrxR2 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Guangxi University

Curated by ChEMBL
LigandPNGBDBM50240382(1,4-dihydroxyanthracene-9,10-dione | quinizarin | ...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of topoisomerase 2 in human MCF7 cells assessed as reduction in cell growth measured after 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Guangxi University

Curated by ChEMBL
LigandPNGBDBM50240382(1,4-dihydroxyanthracene-9,10-dione | quinizarin | ...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of topoisomerase 2 in human A549 cells assessed as reduction in cell growth measured after 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Guangxi University

Curated by ChEMBL
LigandPNGBDBM50240382(1,4-dihydroxyanthracene-9,10-dione | quinizarin | ...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of topoisomerase 2 in human HeLa cells assessed as reduction in cell growth measured after 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Guangxi University

Curated by ChEMBL
LigandPNGBDBM50240382(1,4-dihydroxyanthracene-9,10-dione | quinizarin | ...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of topoisomerase 2 in human CNE1 cells assessed as reduction in cell growth measured after 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Guangxi University

Curated by ChEMBL
LigandPNGBDBM50240382(1,4-dihydroxyanthracene-9,10-dione | quinizarin | ...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of topoisomerase 2 in human MDA-MB-231 cells assessed as reduction in cell growth measured after 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha/2-beta(Human)
Guangxi University

Curated by ChEMBL
LigandPNGBDBM50240382(1,4-dihydroxyanthracene-9,10-dione | quinizarin | ...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of topoisomerase 2 in human HepG2 cells assessed as reduction in cell growth measured after 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetTransthyretin(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50240382(1,4-dihydroxyanthracene-9,10-dione | quinizarin | ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of acid-mediated aggregation of TTR V30M mutant (unknown origin) expressed in Escherichia coli pretreated for 30 mins at pH 7 followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50240382(1,4-dihydroxyanthracene-9,10-dione | quinizarin | ...)
Affinity DataIC50: 65nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells using kynuramine as substrate after 20 mins by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50240382(1,4-dihydroxyanthracene-9,10-dione | quinizarin | ...)
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cells using kynuramine as substrate after 20 mins by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50240382(1,4-dihydroxyanthracene-9,10-dione | quinizarin | ...)
Affinity DataKi:  39nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells using kynuramine as substrate after 20 mins by Lineweaver-Bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed