BDBM50001897 1-(4-Chloro-phenyl)-piperazine::CHEMBL114478::pCPP

SMILES Clc1ccc(cc1)N1CCNCC1

InChI Key InChIKey=UNEIHNMKASENIG-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50001897   

TargetBeta-1 adrenergic receptor(Human)
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50001897(CHEMBL114478 | pCPP | 1-(4-Chloro-phenyl)-piperazi...)
Affinity DataIC50: 1.50E+4nMAssay Description:Binding affinity for Beta-1 adrenergic receptor by displacing [3H]dihydroalprenolol, in partially purified membrane fractions from canine ventricular...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Dog)
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50001897(CHEMBL114478 | pCPP | 1-(4-Chloro-phenyl)-piperazi...)
Affinity DataIC50: 7.00E+4nMAssay Description:Binding affinity towards Beta-2 adrenergic receptor by displacing [3H]dihydroalprenolol, in partially purified membrane fractions from canine lung ti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Rat)
Virginia Commonwealth University

Curated by PDSP Ki Database
LigandPNGBDBM50001897(CHEMBL114478 | pCPP | 1-(4-Chloro-phenyl)-piperazi...)
Affinity DataKi:  120nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2011
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50001897(CHEMBL114478 | pCPP | 1-(4-Chloro-phenyl)-piperazi...)
Affinity DataKi:  1.15E+3nMAssay Description:The compound was tested for its binding affinity towards sigma receptor in guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50001897(CHEMBL114478 | pCPP | 1-(4-Chloro-phenyl)-piperazi...)
Affinity DataKi:  2.16E+3nMAssay Description:Compound was tested for the inhibition of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptor expressed in NG 108-15 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed