BDBM50336960 3,4-Dihydro-9-hydroxy-[1]benzothieno[2,3-f]-1,4-thiazepin-5(2H)-one::CHEMBL1672571::kb-NB142-70

SMILES Oc1ccc2sc3c(SCCNC3=O)c2c1

InChI Key InChIKey=DHUAGGSHTKPOHU-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50336960   

TargetSerine/threonine-protein kinase D1(Human)
University of Pittsburgh

LigandPNGBDBM50336960(kb-NB142-70 | CHEMBL1672571 | 3,4-Dihydro-9-hydrox...)
Affinity DataIC50: 28.3nMpH: 7.5 T: 2°CAssay Description:In vitro radiometric kinase assay were conducted using PKD1 from Biomol International, PKD2 from SignalChem and PKD3 Enzo Life Sciences.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase D2(Human)
University of Pittsburgh

LigandPNGBDBM50336960(kb-NB142-70 | CHEMBL1672571 | 3,4-Dihydro-9-hydrox...)
Affinity DataIC50: 58.7nMpH: 7.5 T: 2°CAssay Description:In vitro radiometric kinase assay were conducted using PKD1 from Biomol International, PKD2 from SignalChem and PKD3 Enzo Life Sciences.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase D3(Human)
University of Pittsburgh

LigandPNGBDBM50336960(kb-NB142-70 | CHEMBL1672571 | 3,4-Dihydro-9-hydrox...)
Affinity DataIC50: 53.2nMpH: 7.5 T: 2°CAssay Description:In vitro radiometric kinase assay were conducted using PKD1 from Biomol International, PKD2 from SignalChem and PKD3 Enzo Life Sciences.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase D1(Human)
University of Pittsburgh

LigandPNGBDBM50336960(kb-NB142-70 | CHEMBL1672571 | 3,4-Dihydro-9-hydrox...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of PKD1 autophosphorylation at Ser916 in human PMA-induced LNCAP cells by Western blottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase D1(Human)
University of Pittsburgh

LigandPNGBDBM50336960(kb-NB142-70 | CHEMBL1672571 | 3,4-Dihydro-9-hydrox...)
Affinity DataIC50: 28.3nMAssay Description:Inhibition of human recombinant PKD1 after 10 mins by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase D2(Human)
University of Pittsburgh

LigandPNGBDBM50336960(kb-NB142-70 | CHEMBL1672571 | 3,4-Dihydro-9-hydrox...)
Affinity DataIC50: 59nMAssay Description:Inhibition of PKD2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase D3(Human)
University of Pittsburgh

LigandPNGBDBM50336960(kb-NB142-70 | CHEMBL1672571 | 3,4-Dihydro-9-hydrox...)
Affinity DataIC50: 53nMAssay Description:Inhibition of PKD3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed