BDBM50228077 CHEMBL237122::epierenone

SMILES COC(=O)[C@@H]1CC2=CC(=O)CC[C@]2(C)C2[C@@H]3O[C@@H]3[C@@]3(C)C(CC[C@@]33CCC(=O)O3)C12

InChI Key InChIKey=QBIRIYASLUPKQB-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50228077   

TargetMineralocorticoid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50228077(epierenone | CHEMBL237122)
Affinity DataKi:  124nMAssay Description:Binding affinity to human mineralocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50228077(epierenone | CHEMBL237122)
Affinity DataKi: >1.10E+3nMAssay Description:Binding affinity to human estrogen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50228077(epierenone | CHEMBL237122)
Affinity DataKi:  1.76E+3nMAssay Description:Binding affinity to human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50228077(epierenone | CHEMBL237122)
Affinity DataKi:  8.89E+3nMAssay Description:Binding affinity to human androgen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50228077(epierenone | CHEMBL237122)
Affinity DataKi:  2.94E+4nMAssay Description:Binding affinity to human progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed