BDBM50221718 CHEMBL400538::comaparvin

SMILES CCCc1cc(=O)c2c(O)cc3cc(O)cc(OC)c3c2o1

InChI Key InChIKey=POMCQPYWKLKBSX-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50221718   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Nci-Frederick

Curated by ChEMBL

LigandBDBM50221718(comaparvin | CHEMBL400538)Copy SMILESCopy InChI

Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of ABCG2-mediated drug efflux expressed in human NCI-H460 cellsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
12/31/2012
Entry Details Article
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TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Human)
University of Mississippi

Curated by ChEMBL

LigandBDBM50221718(comaparvin | CHEMBL400538)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of HIF1 activation in human T47D cells by TK-luciferase assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
8/24/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL