BDBM50300340 1-Biphenyl-3-ylmaleimide::CHEMBL567622::cid_930984

SMILES O=C1C=CC(=O)N1c1cccc(c1)-c1ccccc1

InChI Key InChIKey=QQAJYNGNBJIZPR-UHFFFAOYSA-N

Data  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50300340   

Target60S ribosomal protein L19-A(Baker's yeast)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM50300340(cid_930984 | CHEMBL567622 | 1-Biphenyl-3-ylmaleimi...)
Affinity DataEC50:  2.70E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetBcl-2-like protein 11(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50300340(cid_930984 | CHEMBL567622 | 1-Biphenyl-3-ylmaleimi...)
Affinity DataEC50: >3.50E+5nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetVacuolar aminopeptidase 1(Baker's yeast)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM50300340(cid_930984 | CHEMBL567622 | 1-Biphenyl-3-ylmaleimi...)
Affinity DataEC50:  385nMAssay Description:University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetEndothelial PAS domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50300340(cid_930984 | CHEMBL567622 | 1-Biphenyl-3-ylmaleimi...)
Affinity DataIC50: 8.09E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetMonoglyceride lipase(Human)
Louvain Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50300340(cid_930984 | CHEMBL567622 | 1-Biphenyl-3-ylmaleimi...)
Affinity DataIC50: 2.34E+3nMAssay Description:Displacement of [3H]2-OG from human MGL by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Louvain Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50300340(cid_930984 | CHEMBL567622 | 1-Biphenyl-3-ylmaleimi...)
Affinity DataIC50: 4.90E+4nMAssay Description:Displacement of [3H]ethanolamine from human recombinant FAAH by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed