BDBM50238226 2-(5-biphenyl-4-yl-[1,2,4]oxadiazol-3-yl)-pyridine::5-(biphenyl-4-yl)-3-(pyridin-2-yl)-1,2,4-oxadiazole::CHEMBL405317::cid_838877

SMILES c1ccc(cc1)-c1ccc(cc1)-c1nc(no1)-c1ccccn1

InChI Key InChIKey=QWGJENMOSGJVGI-UHFFFAOYSA-N

Data  9 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50238226   

TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50238226(5-(biphenyl-4-yl)-3-(pyridin-2-yl)-1,2,4-oxadiazol...)
Affinity DataEC50: <160nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2011
Entry Details
PCBioAssay
TargetLuciferin 4-monooxygenase(Pennsylania firefly)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50238226(5-(biphenyl-4-yl)-3-(pyridin-2-yl)-1,2,4-oxadiazol...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of luciferin binding site of Photuris pennsylvanica luciferase by noncompetitive KinaseGlo Plus luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetLuciferin 4-monooxygenase(Pennsylania firefly)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50238226(5-(biphenyl-4-yl)-3-(pyridin-2-yl)-1,2,4-oxadiazol...)
Affinity DataIC50: 38nMAssay Description:Inhibition of luciferin binding site of Photuris pennsylvanica luciferase by noncompetitive inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetLuciferin 4-monooxygenase(Common eastern firefly)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50238226(5-(biphenyl-4-yl)-3-(pyridin-2-yl)-1,2,4-oxadiazol...)
Affinity DataIC50: 80nMAssay Description:Inhibition of luciferin binding site of Photinus pyralis luciferase by noncompetitive inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetLuciferin 4-monooxygenase(Pennsylania firefly)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50238226(5-(biphenyl-4-yl)-3-(pyridin-2-yl)-1,2,4-oxadiazol...)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of luciferin binding site of Photuris pennsylvanica luciferase by noncompetitive KinaseGlo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetLuciferin 4-monooxygenase(Common eastern firefly)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50238226(5-(biphenyl-4-yl)-3-(pyridin-2-yl)-1,2,4-oxadiazol...)
Affinity DataIC50: 100nMAssay Description:Inhibition of Photinus pyralis luciferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetLuciferin 4-monooxygenase(Common eastern firefly)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50238226(5-(biphenyl-4-yl)-3-(pyridin-2-yl)-1,2,4-oxadiazol...)
Affinity DataIC50: 140nMAssay Description:Inhibition of Photinus pyralis luciferase by Steady-Glo reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetLuciferin 4-monooxygenase(Common eastern firefly)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50238226(5-(biphenyl-4-yl)-3-(pyridin-2-yl)-1,2,4-oxadiazol...)
Affinity DataIC50: 300nMAssay Description:Inhibition of Photinus pyralis luciferase by BrightGlo reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetLuciferin 4-monooxygenase(Common eastern firefly)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50238226(5-(biphenyl-4-yl)-3-(pyridin-2-yl)-1,2,4-oxadiazol...)
Affinity DataIC50: 500nMAssay Description:Inhibition of Photinus pyralis luciferase by Easy lite assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetLuciferin 4-monooxygenase(Common eastern firefly)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50238226(5-(biphenyl-4-yl)-3-(pyridin-2-yl)-1,2,4-oxadiazol...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of Photinus pyralis luciferase by PK-Light assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed