BDBM50132133 5-p-Tolyl-1H-pyrazole-3-carboxylic acid::CHEMBL341154::cid_818267

SMILES Cc1ccc(cc1)-c1cc([nH]n1)C(O)=O

InChI Key InChIKey=BGTWUOQARPOYER-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50132133   

TargetAlkaline phosphatase, tissue-nonspecific isozyme(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50132133(cid_818267 | CHEMBL341154 | 5-p-Tolyl-1H-pyrazole-...)
Affinity DataIC50: 8.71E+3nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
TargetHydroxycarboxylic acid receptor 2(Rat)
Leiden/Amsterdam Center For Drug Research

Curated by ChEMBL
LigandPNGBDBM50132133(cid_818267 | CHEMBL341154 | 5-p-Tolyl-1H-pyrazole-...)
Affinity DataKi:  3.79E+4nMAssay Description:Inhibition of [3H]-nicotinic acid (20 nM) binding to nicotinic acid receptor in rat spleen membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50132133(cid_818267 | CHEMBL341154 | 5-p-Tolyl-1H-pyrazole-...)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 expressed in Escherichia coli preincubated for 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50132133(cid_818267 | CHEMBL341154 | 5-p-Tolyl-1H-pyrazole-...)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 expressed in Escherichia coli preincubated for 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50132133(cid_818267 | CHEMBL341154 | 5-p-Tolyl-1H-pyrazole-...)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 expressed in Escherichia coli preincubated for 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
University of Belgrade

Curated by ChEMBL
LigandPNGBDBM50132133(cid_818267 | CHEMBL341154 | 5-p-Tolyl-1H-pyrazole-...)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human recombinant carbonic anhydrase 12 expressed in Escherichia coli preincubated for 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed