BDBM50209100 4-hydroxymethylbenzoate::CHEMBL325372::Methyl paraben::Methylparaben::cid_7456::methyl 4-hydroxybenzoate

SMILES COC(=O)c1ccc(cc1)O

InChI Key InChIKey=LXCFILQKKLGQFO-UHFFFAOYSA-N

Data  6 KI  2 IC50  1 EC50

PDB links: 7 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50209100   

TargetGlycogen synthase kinase-3 beta(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50209100(4-hydroxymethylbenzoate | methyl 4-hydroxybenzoate...)
Affinity DataEC50: >3.00E+5nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay
TargetXanthine dehydrogenase/oxidase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50209100(4-hydroxymethylbenzoate | methyl 4-hydroxybenzoate...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of xanthine oxidase-mediated formation of uric acid by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
University of Basel

Curated by ChEMBL
LigandPNGBDBM50209100(4-hydroxymethylbenzoate | methyl 4-hydroxybenzoate...)
Affinity DataIC50: 4.27E+5nMAssay Description:Inhibitory concentration against recombinant rat androgen receptor expressed in Escherichia coli using [3H]methyltrienolone (R 1881)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50209100(4-hydroxymethylbenzoate | methyl 4-hydroxybenzoate...)
Affinity DataKi:  780nMAssay Description:Inhibition of human carbonic anhydrase 7 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50209100(4-hydroxymethylbenzoate | methyl 4-hydroxybenzoate...)
Affinity DataKi:  820nMAssay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50209100(4-hydroxymethylbenzoate | methyl 4-hydroxybenzoate...)
Affinity DataKi:  2.60E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50209100(4-hydroxymethylbenzoate | methyl 4-hydroxybenzoate...)
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 14(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50209100(4-hydroxymethylbenzoate | methyl 4-hydroxybenzoate...)
Affinity DataKi:  4.10E+3nMAssay Description:Inhibition of human carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50209100(4-hydroxymethylbenzoate | methyl 4-hydroxybenzoate...)
Affinity DataKi:  5.50E+3nMAssay Description:Inhibition of human carbonic anhydrase 9 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed