BDBM50106345 4-(4-Methyl-piperazin-1-yl)-phenylamine::CHEMBL341473::cid_737253

SMILES CN1CCN(CC1)c1ccc(N)cc1

InChI Key InChIKey=MOZNZNKHRXRLLF-UHFFFAOYSA-N

Data  2 KI  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50106345   

TargetFocal adhesion kinase 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50106345(CHEMBL341473 | cid_737253 | 4-(4-Methyl-piperazin-...)
Affinity DataIC50: 2.75E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2011
Entry Details
PCBioAssay
LigandPNGBDBM50106345(CHEMBL341473 | cid_737253 | 4-(4-Methyl-piperazin-...)
Affinity DataEC50:  3.73E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
TargetProtein-tyrosine kinase 2-beta(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50106345(CHEMBL341473 | cid_737253 | 4-(4-Methyl-piperazin-...)
Affinity DataIC50: 2.83E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
TargetEstrogen receptor beta(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM50106345(CHEMBL341473 | cid_737253 | 4-(4-Methyl-piperazin-...)
Affinity DataIC50: 7.13E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: John A. Katzenellenbogen, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandPNGBDBM50106345(CHEMBL341473 | cid_737253 | 4-(4-Methyl-piperazin-...)
Affinity DataEC50: <5.01E+5nMAssay Description:Agonist activity at recombinant human alpha2c adrenergic receptor expressed in CHOK1 cells co-expressing Gqi5 assessed as induction of cytoplasmic ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandPNGBDBM50106345(CHEMBL341473 | cid_737253 | 4-(4-Methyl-piperazin-...)
Affinity DataKi:  1.51E+3nMAssay Description:Displacement of [3H]-UK14304 from recombinant human alpha2c adrenergic receptor expressed in CHOK1 cell membranes after 30 mins by scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2016
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50106345(CHEMBL341473 | cid_737253 | 4-(4-Methyl-piperazin-...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity against nicotinic receptors from rat brain using [3H]cystine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed