BDBM50132009 3-(2-Oxo-propylidene)-1,3-dihydro-indol-2-one::CHEMBL127205::cid_725903

SMILES CC(=O)C=C1C(=O)Nc2ccccc12

InChI Key InChIKey=AQPYUQKKKCLZAT-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50132009   

TargetEndothelial PAS domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50132009(cid_725903 | CHEMBL127205 | 3-(2-Oxo-propylidene)-...)
Affinity DataIC50: 1.40E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50132009(cid_725903 | CHEMBL127205 | 3-(2-Oxo-propylidene)-...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50132009(cid_725903 | CHEMBL127205 | 3-(2-Oxo-propylidene)-...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human transglutaminase 2 using ZGBC as a substrate after 30 to 60 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetMO15-related protein kinase Pfmrk(malaria parasite P. falciparum)
Institute of Research

Curated by ChEMBL
LigandPNGBDBM50132009(cid_725903 | CHEMBL127205 | 3-(2-Oxo-propylidene)-...)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibitory activity against Plasmodium falciparum cyclin dependent protein kinase, PfmrkMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50132009(cid_725903 | CHEMBL127205 | 3-(2-Oxo-propylidene)-...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed