BDBM50056891 2-Hydroxy-benzoic acid N'-(2-hydroxy-benzoyl)-hydrazide::2-hydroxybenzoic acid 2-(2-hydroxybenzoyl)hydrazide::CHEMBL36303::cid_65303

SMILES Oc1ccccc1C(=O)NNC(=O)c1ccccc1O

InChI Key InChIKey=UORSDGBOJHYJLV-UHFFFAOYSA-N

Data  19 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50056891   

TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50056891(CHEMBL36303 | cid_65303 | 2-Hydroxy-benzoic acid N...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory activity against HIV-1 integrase (preincubated with Mg+2, and drug for 30 min followed by DNA for 1h) in 3''-processing of preassembleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50056891(CHEMBL36303 | cid_65303 | 2-Hydroxy-benzoic acid N...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of recombinant HIV1 integrase-mediated 3'-processing activity in presence of manganeseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50056891(CHEMBL36303 | cid_65303 | 2-Hydroxy-benzoic acid N...)
Affinity DataIC50: 3.33E+5nMAssay Description:Inhibition of recombinant HIV1 integrase strand transfer activity in presence of magnesiumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50056891(CHEMBL36303 | cid_65303 | 2-Hydroxy-benzoic acid N...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of recombinant HIV1 integrase strand transfer activity in presence of manganeseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50056891(CHEMBL36303 | cid_65303 | 2-Hydroxy-benzoic acid N...)
Affinity DataIC50: 3.33E+5nMAssay Description:Inhibition of recombinant HIV1 integrase-mediated 3'-processing activity in presence of magnesiumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50056891(CHEMBL36303 | cid_65303 | 2-Hydroxy-benzoic acid N...)
Affinity DataIC50: 700nMAssay Description:Inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50056891(CHEMBL36303 | cid_65303 | 2-Hydroxy-benzoic acid N...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mn+2, and drug for 30 min followed by DNA for 1h) in 3''-processing of preassembleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50056891(CHEMBL36303 | cid_65303 | 2-Hydroxy-benzoic acid N...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mg+2, and DNA on ice for 15 min followed by drug for 1h) in strand transfer of postas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50056891(CHEMBL36303 | cid_65303 | 2-Hydroxy-benzoic acid N...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mn+2, and DNA on ice for 15 min followed by drug for 1h) in 3'' processing of postass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50056891(CHEMBL36303 | cid_65303 | 2-Hydroxy-benzoic acid N...)
Affinity DataIC50: 700nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mn+2, and drug for 30 min followed by DNA for 1h) in strand transfer of preassembleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlbumin(Bovine)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50056891(CHEMBL36303 | cid_65303 | 2-Hydroxy-benzoic acid N...)
Affinity DataIC50: 9.39E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50056891(CHEMBL36303 | cid_65303 | 2-Hydroxy-benzoic acid N...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mn+2, and DNA on ice for 15 min followed by drug for 1h) in strand transfer of postas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50056891(CHEMBL36303 | cid_65303 | 2-Hydroxy-benzoic acid N...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mg+2, and DNA on ice for 15 min followed by drug for 1h) in 3'' processing of postass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50056891(CHEMBL36303 | cid_65303 | 2-Hydroxy-benzoic acid N...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory activity against HIV-1 integrase (pre-incubated with Mg+2, and drug for 30 min followed by DNA for 1h) in strand transfer of preassembleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50056891(CHEMBL36303 | cid_65303 | 2-Hydroxy-benzoic acid N...)
Affinity DataIC50: 2.07E+3nMAssay Description:Inhibition of HIV-1 integrase enzyme at 3`- processing stage of DNA integrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50056891(CHEMBL36303 | cid_65303 | 2-Hydroxy-benzoic acid N...)
Affinity DataIC50: 730nMAssay Description:Inhibitory concentration as 50% inhibition of HIV-1 integrase enzyme at strand transfer stage of DNA integration.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50056891(CHEMBL36303 | cid_65303 | 2-Hydroxy-benzoic acid N...)
Affinity DataIC50: 730nMAssay Description:Inhibition of HIV-1 integrase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50056891(CHEMBL36303 | cid_65303 | 2-Hydroxy-benzoic acid N...)
Affinity DataIC50: 2.07E+3nMAssay Description:Inhibition of HIV-1 integrase enzyme by 3'-processing methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetT cell receptor alpha variable 4(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50056891(CHEMBL36303 | cid_65303 | 2-Hydroxy-benzoic acid N...)
Affinity DataIC50: 9.39E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay