BDBM50238208 2,4-dimethoxy-N-(5-methylpyridin-2-yl)benzamide::CHEMBL405914::cid_649849

SMILES COc1ccc(C(=O)Nc2ccc(C)cn2)c(OC)c1

InChI Key InChIKey=DXZWNXBIUIRQRE-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50238208   

TargetIsoform 2 of Nuclear receptor ROR-alpha (Alpha-2)(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50238208(cid_649849 | CHEMBL405914 | 2,4-dimethoxy-N-(5-met...)
Affinity DataIC50: 2.57E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetSteroidogenic factor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50238208(cid_649849 | CHEMBL405914 | 2,4-dimethoxy-N-(5-met...)
Affinity DataIC50: 1.22E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetIsoform 2 of Nuclear receptor ROR-alpha (Alpha-2)(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50238208(cid_649849 | CHEMBL405914 | 2,4-dimethoxy-N-(5-met...)
Affinity DataIC50: 3.60E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetSteroidogenic factor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50238208(cid_649849 | CHEMBL405914 | 2,4-dimethoxy-N-(5-met...)
Affinity DataIC50: 3.40E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetLuciferin 4-monooxygenase(Heike firefly)
Leiden/Amsterdam Center For Drug Research

Curated by ChEMBL
LigandPNGBDBM50238208(cid_649849 | CHEMBL405914 | 2,4-dimethoxy-N-(5-met...)
Affinity DataIC50: 610nMAssay Description:Inhibition of firefly luciferase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLuciferin 4-monooxygenase(Common eastern firefly)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50238208(cid_649849 | CHEMBL405914 | 2,4-dimethoxy-N-(5-met...)
Affinity DataIC50: 500nMAssay Description:Inhibition of Photinus pyralis luciferase by Steady-Glo reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetLuciferin 4-monooxygenase(Common eastern firefly)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50238208(cid_649849 | CHEMBL405914 | 2,4-dimethoxy-N-(5-met...)
Affinity DataIC50: 200nMAssay Description:Inhibition of Photinus pyralis luciferase by BrightGlo reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetLuciferin 4-monooxygenase(Common eastern firefly)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50238208(cid_649849 | CHEMBL405914 | 2,4-dimethoxy-N-(5-met...)
Affinity DataIC50: 80nMAssay Description:Inhibition of Photinus pyralis luciferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetLuciferin 4-monooxygenase(Common eastern firefly)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50238208(cid_649849 | CHEMBL405914 | 2,4-dimethoxy-N-(5-met...)
Affinity DataIC50: 280nMAssay Description:Inhibition of Photinus pyralis luciferase by Easy lite assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetLuciferin 4-monooxygenase(Common eastern firefly)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50238208(cid_649849 | CHEMBL405914 | 2,4-dimethoxy-N-(5-met...)
Affinity DataIC50: 250nMAssay Description:Inhibition of Photinus pyralis luciferase by PK-Light assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed