BDBM50106922 (E)-1-(2-Hydroxy-4-methoxy-phenyl)-3-phenyl-propenone::(E)-1-(2-Hydroxy-4-methoxyphenyl)-3-phenylprop-2-en-1-one::2-hydroxy-4-methoxychalcone::CHEMBL317469::cid_5380645

SMILES COc1ccc(C(=O)\C=C\c2ccccc2)c(O)c1

InChI Key InChIKey=GUNGQVJAKLIYDG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50106922   

TargetMitochondrial import inner membrane translocase subunit TIM10(Baker's yeast)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50106922(cid_5380645 | (E)-1-(2-Hydroxy-4-methoxyphenyl)-3-...)
Affinity DataIC50: 3.42E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay
TargetCyclin-dependent kinase 1(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50106922(cid_5380645 | (E)-1-(2-Hydroxy-4-methoxyphenyl)-3-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Cdk1/cyclin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50106922(cid_5380645 | (E)-1-(2-Hydroxy-4-methoxyphenyl)-3-...)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as Hoechst 33342 accumulation preincubated for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50106922(cid_5380645 | (E)-1-(2-Hydroxy-4-methoxyphenyl)-3-...)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of BCRP in human MCF7/MX cells assessed as Hoechst 33342 accumulation preincubated for 30 mins by FluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed