BDBM50124967 5,6,8,5',6',8'-Hexahydroxy-2,3,2',3'-tetramethyl-2,3,2',3'-tetrahydro-[9,9']bi[benzo[g]chromenyl]-4,4'-dione::CHEMBL162783::cid_53277

SMILES CC1Oc2cc3c(c(O)cc(O)c3c(O)c2C(=O)C1C)-c1c(O)cc(O)c2c(O)c3C(=O)C(C)C(C)Oc3cc12

InChI Key InChIKey=RHNVLFNWDGWACV-UHFFFAOYSA-N

Data  6 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50124967   

LigandPNGBDBM50124967(CHEMBL162783 | cid_53277 | 5,6,8,5',6',8'-Hexahydr...)
Affinity DataIC50: 2.15E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50124967(CHEMBL162783 | cid_53277 | 5,6,8,5',6',8'-Hexahydr...)
Affinity DataEC50:  1.74E+3nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2011
Entry Details
PCBioAssay
TargetIntegrase(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124967(CHEMBL162783 | cid_53277 | 5,6,8,5',6',8'-Hexahydr...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of HIV-1 integrase in coupled transfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124967(CHEMBL162783 | cid_53277 | 5,6,8,5',6',8'-Hexahydr...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of HIV-1 integrase in coupled transfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124967(CHEMBL162783 | cid_53277 | 5,6,8,5',6',8'-Hexahydr...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of HIV-1 integrase in strand transfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50124967(CHEMBL162783 | cid_53277 | 5,6,8,5',6',8'-Hexahydr...)
Affinity DataIC50: 4.41E+4nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coli EC538 assessed as reduction in N-formylkynurenine formation using L-tryptophan as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50124967(CHEMBL162783 | cid_53277 | 5,6,8,5',6',8'-Hexahydr...)
Affinity DataIC50: 4.86E+4nMAssay Description:Inhibition of recombinant human TDO2 expressed in Escherichia coli BL21 (DE3) assessed as reduction in N-formylkynurenine formation using L-tryptopha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed