BDBM50240899 5,7-Dihydroxy-2-(4-hydroxy-phenyl)-3-methoxy-chromen-4-one::CHEMBL165064::cid_5280862::kaempferol-3-O-methyl ether

SMILES COc1c(oc2cc(O)cc(O)c2c1=O)-c1ccc(O)cc1

InChI Key InChIKey=VJJZJBUCDWKPLC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50240899   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50240899(cid_5280862 | 5,7-Dihydroxy-2-(4-hydroxy-phenyl)-3...)
Affinity DataIC50: 5.41E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2011
Entry Details
PCBioAssay
TargetBcl-2-like protein 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50240899(cid_5280862 | 5,7-Dihydroxy-2-(4-hydroxy-phenyl)-3...)
Affinity DataIC50: 1.09E+5nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2011
Entry Details
PCBioAssay
TargetCytochrome P450 2D6(Human)
Toyama Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50240899(cid_5280862 | 5,7-Dihydroxy-2-(4-hydroxy-phenyl)-3...)
Affinity DataIC50: 4.63E+3nMAssay Description:Inhibition of human CYP2D6 by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Toyama Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50240899(cid_5280862 | 5,7-Dihydroxy-2-(4-hydroxy-phenyl)-3...)
Affinity DataIC50: 3.62E+4nMAssay Description:Inhibition of human CYP3A4 by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
Universidad Nacional De C£Rdoba

Curated by ChEMBL
LigandPNGBDBM50240899(cid_5280862 | 5,7-Dihydroxy-2-(4-hydroxy-phenyl)-3...)
Affinity DataIC50: 4nMAssay Description:Inhibition of bovine milk xanthine oxidase using xanthine as substrate preincubated for 15 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50240899(cid_5280862 | 5,7-Dihydroxy-2-(4-hydroxy-phenyl)-3...)
Affinity DataIC50: 1.61E+4nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed