BDBM50218922 2-Phenyl-2,5-dihydro-pyrazolo[3,4-c]quinolin-4-one::2-phenyl-2H-pyrazolo[3,4-c]quinolin-4(5H)-one::CHEMBL241987::cid_4962866

SMILES O=c1[nH]c2ccccc2c2cn(nc12)-c1ccccc1

InChI Key InChIKey=ISMLHIIGSRUCOQ-UHFFFAOYSA-N

Data  6 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50218922   

TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50218922(CHEMBL241987 | cid_4962866 | 2-Phenyl-2,5-dihydro-...)
Affinity DataEC50:  1.26E+5nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2011
Entry Details
PCBioAssay
TargetAdenosine receptor A3(Human)
Universita' Di Firenze

Curated by ChEMBL
LigandPNGBDBM50218922(CHEMBL241987 | cid_4962866 | 2-Phenyl-2,5-dihydro-...)
Affinity DataKi:  30.8nMAssay Description:Displacement of specific [125I]AB-MECA binding at human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Universita' Di Firenze

Curated by ChEMBL
LigandPNGBDBM50218922(CHEMBL241987 | cid_4962866 | 2-Phenyl-2,5-dihydro-...)
Affinity DataKi:  30.8nMAssay Description:Displacement of [125I]I-AB-MECA from human recombinant adenosine A3 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50218922(CHEMBL241987 | cid_4962866 | 2-Phenyl-2,5-dihydro-...)
Affinity DataKi:  203nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50218922(CHEMBL241987 | cid_4962866 | 2-Phenyl-2,5-dihydro-...)
Affinity DataKi:  203nMAssay Description:Displacement of [3H]DPCPX from human recombinant adenosine A1 receptor expressed in CHO cell membranes by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Bovine)
Universita' Di Firenze

Curated by ChEMBL
LigandPNGBDBM50218922(CHEMBL241987 | cid_4962866 | 2-Phenyl-2,5-dihydro-...)
Affinity DataKi:  2.10E+3nMAssay Description:Displacement of specific [3H]CHA binding at adenosine A1 receptor in bovine brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Universita' Di Firenze

Curated by ChEMBL
LigandPNGBDBM50218922(CHEMBL241987 | cid_4962866 | 2-Phenyl-2,5-dihydro-...)
Affinity DataKi:  8.60E+3nMAssay Description:Displacement of specific [3H]-CGS- 21680 binding at Adenosine A2A receptor in bovine striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed