BDBM200295 AB00053825_07::Ethidium bromide::cid_3624

SMILES CC[n+]1c(-c2ccccc2)c2cc(N)ccc2c2ccc(N)cc12

InChI Key InChIKey=QTANTQQOYSUMLC-UHFFFAOYSA-O

Data  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 200295   

TargetCystic fibrosis transmembrane conductance regulator(Human)
Southern Research Institute

Curated by PubChem BioAssay
LigandPNGBDBM200295(Ethidium bromide | AB00053825_07 | cid_3624)
Affinity DataEC50: >5.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2016
Entry Details
PCBioAssay
TargetDNA helicase [35-727](malaria parasite P. falciparum)
International Centre For Genetic Engineering and Biotechnology

LigandPNGBDBM200295(Ethidium bromide | AB00053825_07 | cid_3624)
Affinity DataIC50: 3.10E+3nMpH: 8.0 T: 2°CAssay Description:The hydrolysis of ATP catalyzed by PfUDN was assayed by measuring the formation of Pi from [γ-32P] ATP. The reaction mixture of 10 μl conta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2017
Entry Details Article
PubMed
TargetDNA helicase [35-727](malaria parasite P. falciparum)
International Centre For Genetic Engineering and Biotechnology

LigandPNGBDBM200295(Ethidium bromide | AB00053825_07 | cid_3624)
Affinity DataIC50: 4.80E+3nMpH: 8.0 T: 2°CAssay Description:Helicase assay was demonstrated using the purified fraction of PfUDN. The specially designed partial duplex substrate consisted of a 32P-labelled 47-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2017
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM200295(Ethidium bromide | AB00053825_07 | cid_3624)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase using 25 ug/mL of Poly(rA).p(dT) (12 to 18) as substrate after 30 mins by single point PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM200295(Ethidium bromide | AB00053825_07 | cid_3624)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase using 0.5 ug/mL of Poly(rA).p(dT) (12 to 18) as substrate after 30 mins by single point PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Missouri

Curated by ChEMBL
LigandPNGBDBM200295(Ethidium bromide | AB00053825_07 | cid_3624)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase using 0.05 ug/mL of Poly(rA).p(dT) (12 to 18) as substrate after 30 mins by single point PCR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed