BDBM50237953 2-(4-allyl-5-(3-chlorophenyl)-4H-1,2,4-triazol-3-ylthio)-1-(3,4-dihydroxyphenyl)ethanone::2-[4-allyl-5-(3-chlorophenyl)-4H-[1,2,4]triazol-3-ylsulfanyl]-1-(3,4-dihydroxyphenyl)ethanone::CHEMBL400144::cid_1398345

SMILES Oc1ccc(cc1O)C(=O)CSc1nnc(-c2cccc(Cl)c2)n1CC=C

InChI Key InChIKey=DZTFRDMOGLIUFL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50237953   

TargetAlkaline phosphatase, tissue-nonspecific isozyme(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50237953(cid_1398345 | 2-[4-allyl-5-(3-chlorophenyl)-4H-[1,...)
Affinity DataIC50: 2.07E+4nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
TargetAlkaline phosphatase, germ cell type(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50237953(cid_1398345 | 2-[4-allyl-5-(3-chlorophenyl)-4H-[1,...)
Affinity DataIC50: 6.62E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
TargetProtein tyrosine phosphatase type IVA 3(Human)
Sejong University

Curated by ChEMBL
LigandPNGBDBM50237953(cid_1398345 | 2-[4-allyl-5-(3-chlorophenyl)-4H-[1,...)
Affinity DataIC50: 4.38E+4nMAssay Description:Inhibition of human PRL3 expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Sejong University

Curated by ChEMBL
LigandPNGBDBM50237953(cid_1398345 | 2-[4-allyl-5-(3-chlorophenyl)-4H-[1,...)
Affinity DataIC50: 3.28E+3nMAssay Description:Inhibition of Cdc25A (336-523) expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Sejong University

Curated by ChEMBL
LigandPNGBDBM50237953(cid_1398345 | 2-[4-allyl-5-(3-chlorophenyl)-4H-[1,...)
Affinity DataIC50: 4.67E+3nMAssay Description:Inhibition of Cdc25B (378-566) expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed