BDBM50278145 CHEMBL469546::N-(2,4-dichlorobenzyl)-1-(mesitylsulfonyl)piperidine-4-carboxamide::cid_1306384

SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N1CCC(CC1)C(=O)NCc1ccc(Cl)cc1Cl

InChI Key InChIKey=HRKVSQNBSGFSQY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50278145   

TargetBifunctional epoxide hydrolase 2(Human)
Columbia University Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50278145(cid_1306384 | CHEMBL469546 | N-(2,4-dichlorobenzyl...)
Affinity DataIC50: 8.10nMAssay Description:Data Source: Columbia University Molecular Screening Center Source (MLSCN Center Name): Columbia University Molecular Screening Center Center Affilia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2011
Entry Details
PCBioAssay
TargetBifunctional epoxide hydrolase 2(Human)
Columbia University Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50278145(cid_1306384 | CHEMBL469546 | N-(2,4-dichlorobenzyl...)
Affinity DataIC50: 20nMAssay Description:Inhibition of epoxide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Columbia University Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50278145(cid_1306384 | CHEMBL469546 | N-(2,4-dichlorobenzyl...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed