BDBM420305 Z-FA-FM::Z-FA-FMK

SMILES CC(NC(=O)C(Cc1ccccc1)NC(=O)OCc1ccccc1)C(=O)CF

InChI Key InChIKey=ASXVEBPEZMSPHB-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 420305   

TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes of Health

LigandPNGBDBM420305(Z-FA-FMK | Z-FA-FM)
Affinity DataIC50: 1.14E+4nMAssay Description:The 3CLpro enzyme assay was developed in 384-well black, medium binding microplates (Greiner Bio-One, Monroe, NC, USA) with a total volume of 20 _...More data for this Ligand-Target Pair
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In Depth
Date in BDB:
9/21/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes of Health

LigandPNGBDBM420305(Z-FA-FMK | Z-FA-FM)
Affinity DataEC50:  130nMAssay Description:SARS-CoV-2 CPE assay was conducted at Southern Research Institute (Birmingham, AL) as described in previous reports30, 31. In brief, high ACE2 expres...More data for this Ligand-Target Pair
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In Depth
Date in BDB:
9/21/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes of Health

LigandPNGBDBM420305(Z-FA-FMK | Z-FA-FM)
Affinity DataIC50: 1.14E+4nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
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In Depth
Date in BDB:
1/27/2022
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes of Health

LigandPNGBDBM420305(Z-FA-FMK | Z-FA-FM)
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of SARS-CoV-2 3CL protease expressed in Escherichia coli using Dabcyl-KTSAVLQSGFRKM-E(Edans)-NH2 as substrate preincubated for 30 mins fol...More data for this Ligand-Target Pair
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In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Institutes of Health

LigandPNGBDBM420305(Z-FA-FMK | Z-FA-FM)
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length SARS-CoV-2 3CLpro expressed in Escherichia coli BL21(DE3) using (KTSAVLQSGFRKME) as fluo...More data for this Ligand-Target Pair
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In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed