BDBM50243934 2-[(4-Morpholin-4-ylphenyl)amino]-4-[(2,3,6-trifluorobenzyl)amino]pyrimidine-5-carboxamide::AS-1617612::CHEMBL487451::CHEMBL488307::YM-3416

SMILES NC(=O)c1cnc(Nc2ccc(cc2)N2CCOCC2)nc1NCc1c(F)cc(F)cc1F

InChI Key InChIKey=REUWMZJCJWNNNQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50243934   

TargetSignal transducer and activator of transcription 6(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50243934(CHEMBL487451 | CHEMBL488307 | AS-1617612 | 2-[(4-M...)
Affinity DataIC50: 88nMAssay Description:Inhibition of STAT6 activation in FW4 reporter cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 6(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50243934(CHEMBL487451 | CHEMBL488307 | AS-1617612 | 2-[(4-M...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of STAT6 activation in FW4 reporter cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed