BDBM50056102 (R)-1-(1-(3,3-dimethyl-2-oxobutyl)-2-oxo-5-(pyridin-2-yl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-3-(3-(methylamino)phenyl)urea::1-[(R)-1-(3,3-Dimethyl-2-oxo-butyl)-2-oxo-5-pyridin-2-yl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-3-(3-methylamino-phenyl)-urea::CHEMBL324547::YF-476

SMILES CNc1cccc(NC(=O)N[C@@H]2N=C(c3ccccn3)c3ccccc3N(CC(=O)C(C)(C)C)C2=O)c1

InChI Key InChIKey=YDZYKNJZCVIKPP-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50056102   

TargetCholecystokinin receptor type A(Rat)
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50056102(YF-476 | 1-[(R)-1-(3,3-Dimethyl-2-oxo-butyl)-2-oxo...)
Affinity DataIC50: 502nMAssay Description:Inhibitory concentration against radioligand [3 H]L-364,718 binding to gastrin/Cholecystokinin type A receptor from rat pancreasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Rat)
Ferring Research Institute

Curated by ChEMBL
LigandPNGBDBM50056102(YF-476 | 1-[(R)-1-(3,3-Dimethyl-2-oxo-butyl)-2-oxo...)
Affinity DataIC50: 0.100nMAssay Description:Inhibitory concentration against radioligand [125I]CCK-8 binding to gastrin/Cholecystokinin type B receptor from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50056102(YF-476 | 1-[(R)-1-(3,3-Dimethyl-2-oxo-butyl)-2-oxo...)
Affinity DataKi:  0.140nMAssay Description:Displacement of [3H]BH-CCK-8S from human recombinant CCK2 receptor expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50056102(YF-476 | 1-[(R)-1-(3,3-Dimethyl-2-oxo-butyl)-2-oxo...)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]L-364718 from human recombinant CCK1 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Guinea pig)
James Black Foundation

Curated by ChEMBL
LigandPNGBDBM50056102(YF-476 | 1-[(R)-1-(3,3-Dimethyl-2-oxo-butyl)-2-oxo...)
Affinity DataKi:  398nMAssay Description:Displacement of [125I]BH-CCK-8S from CC1 receptor expressed in guinea pig pancreatic cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed