BDBM50038881 CHEMBL294803::Y-29794::[2-(8-Dimethylamino-octylsulfanyl)-6-isopropyl-pyridin-3-yl]-thiophen-2-yl-methanone

SMILES CC(C)c1ccc(C(=O)c2cccs2)c(SCCCCCCCCN(C)C)n1

InChI Key InChIKey=HAGHKJDWBDSFKC-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50038881   

TargetProlyl endopeptidase(Human)
Zeria Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50038881([2-(8-Dimethylamino-octylsulfanyl)-6-isopropyl-pyr...)
Affinity DataIC50: 3.50E+3nMAssay Description:In vitro inhibitory activity against purified prolyl endopeptidase (PEP) from canine brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Rat)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50038881([2-(8-Dimethylamino-octylsulfanyl)-6-isopropyl-pyr...)
Affinity DataKi:  0.950nMAssay Description:Inhibition of POP in rat brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed