BDBM504319 US11040968, Example 001::US11136324, Example 1::WX001

SMILES Cc1cc(F)c(cc1-n1cnc(c1)C1CC1)C(=O)Nc1cccc(n1)-c1nnc2CCCn12

InChI Key InChIKey=GYLGPTHQOWJVDX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 504319   

LigandPNGBDBM504319(WX001 | US11040968, Example 001 | US11136324, Exam...)
Affinity DataIC50: 1.82nMAssay Description:Primary reaction buffer solution: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOTreatme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2021
Entry Details
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LigandPNGBDBM504319(WX001 | US11040968, Example 001 | US11136324, Exam...)
Affinity DataIC50: 6nMAssay Description:In this test, the fluorescence-resonance energy transfer (TR-FRET) method was used to determine the inhibition effect of the test compounds on ASK1 k...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent