BDBM50027366 Ketazocine::US10081602, Example Ketazocine::US10865186, Compound Ketazocine::US9688638, Ketazocine::WIN-34276
SMILES [H][C@@]12[C@H](C)[C@@](C)(CCN1CC1CC1)c1cc(O)ccc1C2=O
InChI Key InChIKey=HQBZLVPZOGIAIQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50027366
Affinity DataIC50: 5.60nMpH: 7.5Assay Description:The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K...More data for this Ligand-Target Pair
Affinity DataIC50: 8.40nMpH: 7.5Assay Description:The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K...More data for this Ligand-Target Pair
Affinity DataEC50: 0.550nMAssay Description:Inhibition of cAMP accumulation by select compounds was measured in forskolin-stimulated CHO-K1 cells stably expressing KOR. CHO-K1 cells stably expr...More data for this Ligand-Target Pair
Affinity DataEC50: 3.30nMAssay Description:Activity at human cloned kappa opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 21nMAssay Description:Activity at human cloned mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Activity at human cloned mu opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 8.40nMpH: 7.5 T: 2°CAssay Description:Competition binding experiments were conducted by incubating membrane protein to equilibrium in triplicate in the presence of a fixed concentration o...More data for this Ligand-Target Pair
Affinity DataEC50: 0.550nMAssay Description:Inhibition of cAMP accumulation by select compounds was measured in forskolin-stimulated CHO-K1 cells stably expressing KOR. CHO-K1 cells stably expr...More data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]U69593 form kappa opioid receptor in guinea pig brainMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMpH: 7.5Assay Description:The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K...More data for this Ligand-Target Pair
Affinity DataKi: 1.30nM ΔG°: -12.1kcal/mole IC50: 5.60nMpH: 7.5 T: 2°CAssay Description:Competition binding experiments were conducted by incubating membrane protein to equilibrium in triplicate in the presence of a fixed concentration o...More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K...More data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Displacement of [3H]DAMGO form mu opioid receptor in guinea pig brainMore data for this Ligand-Target Pair