BDBM50041303 1-[3-(4-Isopropyl-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct-2-yl]-propan-1-one::CHEMBL278122::WF-31

SMILES CCC(=O)C1C2CCC(CC1c1ccc(cc1)C(C)C)N2C

InChI Key

Data  8 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50041303   

TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50041303(WF-31 | CHEMBL278122 | 1-[3-(4-Isopropyl-phenyl)-8...)
Affinity DataIC50: 440nMAssay Description:Displacement of [125I]RTI-55 from dopamine transporter of rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50041303(WF-31 | CHEMBL278122 | 1-[3-(4-Isopropyl-phenyl)-8...)
Affinity DataIC50: 436nMAssay Description:Inhibitory activity in displacing [125I]- RTI-55 binding to dopamine transporter in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50041303(WF-31 | CHEMBL278122 | 1-[3-(4-Isopropyl-phenyl)-8...)
Affinity DataIC50: 436nMAssay Description:Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50041303(WF-31 | CHEMBL278122 | 1-[3-(4-Isopropyl-phenyl)-8...)
Affinity DataKi:  36nMAssay Description:Displacement of [3H]paroxetine from Serotonin transporter of rat frontal cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50041303(WF-31 | CHEMBL278122 | 1-[3-(4-Isopropyl-phenyl)-8...)
Affinity DataKi:  36nMAssay Description:Affinity for the displacement of [3H]paroxetine binding to serotonin transporter (SERT) in rat frontal cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50041303(WF-31 | CHEMBL278122 | 1-[3-(4-Isopropyl-phenyl)-8...)
Affinity DataKi:  36nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50041303(WF-31 | CHEMBL278122 | 1-[3-(4-Isopropyl-phenyl)-8...)
Affinity DataKi:  309nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50041303(WF-31 | CHEMBL278122 | 1-[3-(4-Isopropyl-phenyl)-8...)
Affinity DataKi:  669nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50041303(WF-31 | CHEMBL278122 | 1-[3-(4-Isopropyl-phenyl)-8...)
Affinity DataKi:  683nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details
PubMed
TargetTransporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50041303(WF-31 | CHEMBL278122 | 1-[3-(4-Isopropyl-phenyl)-8...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-nisoxatine from Norepinephrine transporter of rat forebrain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50041303(WF-31 | CHEMBL278122 | 1-[3-(4-Isopropyl-phenyl)-8...)
Affinity DataKi: >1.00E+4nMAssay Description:Affinity for the displacement of [3H]paroxetine binding to norepinephrine transporter (NET) in rat frontal cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed