BDBM50263044 CHEMBL476960::Voglibose

SMILES C1[C@@H]([C@@H]([C@H]([C@@H]([C@]1(CO)O)O)O)O)NC(CO)CO

InChI Key InChIKey=FZNCGRZWXLXZSZ-UHFFFAOYSA-N

Data  33 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 33 hits for monomerid = 50263044   

TargetLysosomal alpha-glucosidase(Rat)
Kinki University

Curated by ChEMBL
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of rat intestinal maltaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Human)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human lysosomal alpha-glucosidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetGlycogen debranching enzyme(Rabbit)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of rabbit muscle amylo-1,6-glucosidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Human)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 70nMAssay Description:Inhibition of maltase in human Caco-2 cell model system after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 370nMAssay Description:Inhibition of rat intestinal sucrase using sucrose as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of rat intestinal isomaltase using isomaltase as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Kinki University

Curated by ChEMBL
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 120nMAssay Description:Inhibition of rat intestinal maltase using moltose as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 200nMAssay Description:Inhibition of rat intestinal sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of rat intestinal isomaltaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 70nMAssay Description:Inhibition of rat intestinal brush border membrane sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetMaltase-glucoamylase(Human)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human intestinal maltase using maltose as substrate incubated for 30 mins and immediately heated for 2 mins by glucose oxidase methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 200nMAssay Description:Inhibition of sucrase in rat small intestinal brush border membrane vesicles using sucrose as substrate incubated for 30 mins by glucose-oxidase meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Kinki University

Curated by ChEMBL
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of maltase in rat small intestinal brush border membrane vesicles using maltose as substrate incubated for 30 mins by glucose-oxidase meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Kinki University

Curated by ChEMBL
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 120nMAssay Description:Inhibition of Wistar rat intestinal maltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 160nMAssay Description:Inhibition of rat intestinal brush border membrane isomaltaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Kinki University

Curated by ChEMBL
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 110nMAssay Description:Inhibition of rat intestinal brush border membrane maltaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of rat small intestinal sucrase after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Kinki University

Curated by ChEMBL
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 200nMAssay Description:Inhibition of rat small intestinal maltase after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of rat small intestinal isomaltase after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of rat small intestinal isomaltase after 30 mins by glucose-oxidase methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 200nMAssay Description:Inhibition of rat small intestinal sucrase after 30 mins by glucose-oxidase methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Kinki University

Curated by ChEMBL
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of rat small intestinal maltase after 30 mins by glucose-oxidase methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 370nMAssay Description:Inhibition of Wistar rat small intestine sucrase after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of Wistar rat small intestine isomaltase after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Kinki University

Curated by ChEMBL
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 180nMAssay Description:Inhibition of Wistar rat small intestine maltase after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetMaltase-glucoamylase(Human)
Kindai University

Curated by ChEMBL
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human small intestine microsomal maltase using maltose as substrate incubated for 30 mins by glucose-oxidase methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2017
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 300nMAssay Description:Inhibition of rat intestinal sucrase using sucrose as substrate incubated for 30 mins by glucose-oxidase methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2017
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 370nMAssay Description:Inhibition of Wistar rat intestinal sucrase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50263044(Voglibose | CHEMBL476960)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of Wistar rat intestinal isomaltase assessed as inhibition of D-glucose release after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2016
Entry Details Article
PubMed