BDBM50391109 CHEMBL179166::Sodium orthovanadate (SOV)::Vanadates

SMILES [O-][V](=O)([O-])[O-]

InChI Key InChIKey=LSGOVYNHVSXFFJ-UHFFFAOYSA-N

Data  73 IC50

PDB links: 130 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 73 hits for monomerid = 50391109   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Hebei University

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant human PTP1B expressed in Escherichia coli using p-nitrophenyl phosphate as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/26/2021
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TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of SHP2 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/25/2021
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TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 81nMAssay Description:Inhibition of SHP2 (unknown origin) using pNPP as substrate after 30 minsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/26/2021
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TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Shanghai Jiao Tong University (Sjtu)

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 18nMAssay Description:Inhibition of TCPTP (unknown origin) using pNPP as substrate after 30 minsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/26/2021
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TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Hebei University

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 62nMAssay Description:Inhibition of PTP1B (unknown origin) using pNPP as substrate after 30 minsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/26/2021
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TargetReceptor-type tyrosine-protein phosphatase S(Human)
Hebei University

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human PTPsigma expressed in Escherichia coli using p-nitrophenyl phosphate as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

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Date in BDB:
2/26/2021
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TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Shanghai Jiao Tong University (Sjtu)

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant human TCPTP expressed in Escherichia coli using p-nitrophenyl phosphate as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/26/2021
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TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Shanghai Jiao Tong University (Sjtu)

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant human TCPTP expressed in Escherichia coli using p-nitrophenyl phosphate as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/26/2021
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TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Hebei University

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant human PTP1B expressed in Escherichia coli using p-nitrophenyl phosphate as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/26/2021
Entry Details Article
Copy Entry DOIPubMedPDB3D Structure (crystal)
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TargetReceptor-type tyrosine-protein phosphatase S(Human)
Hebei University

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human PTPsigma expressed in Escherichia coli using p-nitrophenyl phosphate as substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/26/2021
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TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 2.63E+3nMAssay Description:Inhibition of SHP1 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

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CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/25/2021
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TargetTyrosyl-DNA phosphodiesterase 1(Human)
Russian Academy of Sciences

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) expressed in Escherichia coli Rosetta2(DE3) using 3'-FITC labeled 13-mer DNA as substrate by Gyrasol ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

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CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/28/2021
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TargetTyrosyl-DNA phosphodiesterase 2(Human)
Russian Academy of Sciences

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 4.00E+7nMAssay Description:Inhibition of human recombinant TDP2 using chromogenic substrate T5PNP by microplate reader analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/28/2021
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TargetM-phase inducer phosphatase 2(Human)
Yanbian University College of Pharmacy

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 210nMAssay Description:Inhibition of human recombinant GST-tagged CDC25B expressed in Escherichia coli BL21 (DE3) using pNPP as substrate measured for 2 mins by colorimetri...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/20/2021
Entry Details Article
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TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of human recombinant GST-tagged SHP1 (catalytic domain 244 to 570 residues) expressed in Escherichia coli BL21 (DE3) using pNPP as substra...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/20/2021
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TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant GST-tagged SHP2 (catalytic domain 1116 to 2162 residues) expressed in Escherichia coli BL21 (DE3) using pNPP as subst...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/20/2021
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TargetReceptor-type tyrosine-protein phosphatase F(Human)
Yanbian University College of Pharmacy

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human recombinant GST-tagged LAR (catalytic domain 1275 to 1613 residues) expressed in Escherichia coli BL21 (DE3) using pNPP as substr...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/20/2021
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TargetReceptor-type tyrosine-protein phosphatase F(Human)
Yanbian University College of Pharmacy

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of LAR (unknown origin) using pNPP as substrateMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/18/2021
Entry Details Article
Copy Entry DOIPubMed
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TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 2.61E+4nMAssay Description:Inhibition of SHP1 (unknown origin) using pNPP as substrateMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/18/2021
Entry Details Article
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TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Hebei University

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 2.94E+3nMAssay Description:Inhibition of N-terminal His-tagged recombinant human PTP1B expressed in Escherichia coliMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
6/26/2023
Entry Details
Copy Entry DOIPubMedPDB3D Structure (crystal)
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TargetDual specificity protein phosphatase 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human VHRMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
12/22/2024
Entry Details
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TargetReceptor-type tyrosine-protein phosphatase S(Human)
Hebei University

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human PTPsigmaMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
12/22/2024
Entry Details
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TargetReceptor-type tyrosine-protein phosphatase F(Human)
Yanbian University College of Pharmacy

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human LARMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
12/22/2024
Entry Details
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TargetM-phase inducer phosphatase 2(Human)
Yanbian University College of Pharmacy

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 2.01E+4nMAssay Description:Inhibition of human CDC25BMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
12/22/2024
Entry Details
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TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Hebei University

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 2.01E+4nMAssay Description:Inhibition of human PTP1BMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
12/22/2024
Entry Details
Copy Entry DOIPubMedPDB3D Structure (crystal)
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TargetM-phase inducer phosphatase 2(Human)
Yanbian University College of Pharmacy

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of CDC25B (unknown origin) by DAS-ELISAMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
4/22/2024
Entry Details
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TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Shanghai Jiao Tong University (Sjtu)

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 890nMAssay Description:Inhibition of TCPTP (unknown origin) by DAS-ELISAMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
4/22/2024
Entry Details
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TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Shanghai Jiao Tong University (Sjtu)

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 1.96E+3nMAssay Description:Inhibition of recombinant human TCPTP (1 to 314 residues) expressed in baculovirus-insect cellsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
6/26/2023
Entry Details
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TargetM-phase inducer phosphatase 2(Human)
Yanbian University College of Pharmacy

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 2.08E+3nMAssay Description:Inhibition of CDC25B (unknown origin) using pNPP as substrateMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/18/2021
Entry Details Article
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TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of SHP1 (unknown origin) using 3-o-methylfluorescein phosphate as substrate by fluorescence assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
8/13/2021
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TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 7.43E+3nMAssay Description:Inhibition of SHP2 (unknown origin) using 3-o-methylfluorescein phosphate as substrate by fluorescence assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
8/13/2021
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TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Hebei University

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant human PTP1B expressed in Escherichia coli using pNPP as substrate preincubated for 15 mins followed by substrate addition a...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
8/13/2021
Entry Details Article
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TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Hebei University

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of PTP1B (unknown origin) assessed as decrease in p-nitrophenolate formation using using pNPP as substrate incubated for 15 mins by spectr...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
8/11/2021
Entry Details Article
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TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Hebei University

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 2.01E+3nMAssay Description:Inhibition of PTP1B A27S mutant (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/25/2021
Entry Details Article
Copy Entry DOIPubMedPDB3D Structure (crystal)
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TargetReceptor-type tyrosine-protein phosphatase F(Human)
Yanbian University College of Pharmacy

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 3.26E+4nMAssay Description:Inhibition of LAR (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/25/2021
Entry Details Article
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TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Hebei University

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 3.09E+3nMAssay Description:Inhibition of GST-fused PTP1B catalytic domain (1 to 321 residues) (unknown origin) expressed in Escherichia coli using pNPP as substrate measured af...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/25/2021
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TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Shanghai Jiao Tong University (Sjtu)

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 2.38E+3nMAssay Description:Inhibition of TCPTP (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
2/25/2021
Entry Details Article
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TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 2.09E+5nMAssay Description:Inhibition of SHP2 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
4/1/2016
Entry Details Article
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TargetReceptor-type tyrosine-protein phosphatase F(Human)
Yanbian University College of Pharmacy

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 2.23E+4nMAssay Description:Inhibition of LAR (unknown origin) assessed as hydrolysis of pNPP to pNP after 30 minsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
12/21/2016
Entry Details Article
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TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of SHP2 (unknown origin) assessed as hydrolysis of pNPP to pNP after 30 minsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
12/21/2016
Entry Details Article
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TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of SHP1 (unknown origin) assessed as hydrolysis of pNPP to pNP after 30 minsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
12/21/2016
Entry Details Article
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TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of SHP1 (unknown origin) using pNPP as substrateMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
10/18/2016
Entry Details Article
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TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of SHP2 (unknown origin) using pNPP as substrateMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
10/18/2016
Entry Details Article
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TargetReceptor-type tyrosine-protein phosphatase F(Human)
Yanbian University College of Pharmacy

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 2.23E+4nMAssay Description:Inhibition of LAR (unknown origin) using pNPP as substrateMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
10/18/2016
Entry Details Article
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TargetM-phase inducer phosphatase 2(Human)
Yanbian University College of Pharmacy

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 8.09E+3nMAssay Description:Inhibition of Cdc25B (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
4/1/2016
Entry Details Article
Copy Entry DOIPubMed
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TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 1.38E+5nMAssay Description:Inhibition of SHP1 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
4/1/2016
Entry Details Article
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TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Hebei University

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 1.52E+4nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy Entry DOIPubMedPDB3D Structure (crystal)
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TargetReceptor-type tyrosine-protein phosphatase F(Human)
Yanbian University College of Pharmacy

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 1.41E+5nMAssay Description:Inhibition of LAR (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
4/1/2016
Entry Details Article
Copy Entry DOIPubMed
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TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 1.65E+4nMAssay Description:Inhibition of SHP1 (unknown origin) using pNPP as substrate by spectrophotometryMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
3/18/2016
Entry Details Article
Copy Entry DOIPubMed
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TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50391109(CHEMBL179166 | Vanadates | Sodium orthovanadate (S...)Copy SMILESCopy InChI

Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of SHP2 (unknown origin) using pNPP as substrate by spectrophotometryMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
3/18/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL