BDBM50024129 5-Amino-1-hydroxymethyl-cyclohexane-1,2,3,4-tetraol::BDBM50241137::CHEMBL9216::Valinolamine::Valiolamine

SMILES C1[C@@H]([C@@H]([C@H]([C@@H]([C@]1(CO)O)O)O)O)N

InChI Key InChIKey=VDLOJRUTNRJDJO-UHFFFAOYSA-N

Data  7 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50024129   

TargetSucrase-isomaltase, intestinal(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50024129(Valiolamine | CHEMBL9216 | Valinolamine | 5-Amino-...)
Affinity DataIC50: 49nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetMaltase-glucoamylase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50024129(Valiolamine | CHEMBL9216 | Valinolamine | 5-Amino-...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibitory activity against porcine maltaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50024129(Valiolamine | CHEMBL9216 | Valinolamine | 5-Amino-...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of rat intestinal brush border membrane maltaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50024129(Valiolamine | CHEMBL9216 | Valinolamine | 5-Amino-...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of rat intestinal brush border membrane isomaltaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50024129(Valiolamine | CHEMBL9216 | Valinolamine | 5-Amino-...)
Affinity DataIC50: 690nMAssay Description:Inhibition of rat intestinal brush border membrane sucraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Human)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50024129(Valiolamine | CHEMBL9216 | Valinolamine | 5-Amino-...)
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of human lysosomal alpha-glucosidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetGlycogen debranching enzyme(Rabbit)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50024129(Valiolamine | CHEMBL9216 | Valinolamine | 5-Amino-...)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of rabbit muscle amylo-1,6-glucosidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed