BDBM22912 VUF 8328::VUF8328::{[3-(1H-imidazol-4-yl)propyl]sulfanyl}methanimidamide

SMILES NC(=N)SCCCc1cnc[nH]1

InChI Key InChIKey=QJUVWGBVEFRHCN-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 22912   

TargetHistamine H3 receptor(Human)
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM22912(VUF8328 | {[3-(1H-imidazol-4-yl)propyl]sulfanyl}me...)
Affinity DataKi:  2.51nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM22912(VUF8328 | {[3-(1H-imidazol-4-yl)propyl]sulfanyl}me...)
Affinity DataKi:  3nMAssay Description:Ligand displacement assays were performed on The SK-N-MC/hH3R cell homogenates. Retained radioactivity was determined by liquid scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2008
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Vu University Amsterdam

Curated by ChEMBL
LigandPNGBDBM22912(VUF8328 | {[3-(1H-imidazol-4-yl)propyl]sulfanyl}me...)
Affinity DataKi:  3.31nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2012
Entry Details
PubMed
TargetHistamine H4 receptor(Human)
Vrije Universiteit Amsterdam

LigandPNGBDBM22912(VUF8328 | {[3-(1H-imidazol-4-yl)propyl]sulfanyl}me...)
Affinity DataKi:  10nMAssay Description:Ligand displacement assays were performed on The SK-N-MC/hH4R cell homogenates. Retained radioactivity was determined by liquid scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2008
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Vrije Universiteit Amsterdam

LigandPNGBDBM22912(VUF8328 | {[3-(1H-imidazol-4-yl)propyl]sulfanyl}me...)
Affinity DataKi:  12.6nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in human SK-N-MC cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed