BDBM50088475 1-(2-Methoxy-phenyl)-3-(2-pyridin-3-yl-quinazolin-4-yl)-urea::CHEMBL70880::VUF-5574

SMILES COc1ccccc1NC(=O)Nc1nc(nc2ccccc12)-c1cccnc1

InChI Key InChIKey=YRAFEJSZTVWUMD-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50088475   

TargetAdenosine receptor A3(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50088475(VUF-5574 | 1-(2-Methoxy-phenyl)-3-(2-pyridin-3-yl-...)
Affinity DataKi:  4nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50088475(VUF-5574 | 1-(2-Methoxy-phenyl)-3-(2-pyridin-3-yl-...)
Affinity DataKi:  4.03E+3nMAssay Description:Binding affinity by its ability to displace [125I]AB-MECA from human adenosine A3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50088475(VUF-5574 | 1-(2-Methoxy-phenyl)-3-(2-pyridin-3-yl-...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-CGS- 21680 binding in adenosine A2A receptor of rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50088475(VUF-5574 | 1-(2-Methoxy-phenyl)-3-(2-pyridin-3-yl-...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DPCPX binding to adenosine A1 receptor of rat brain cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50088475(VUF-5574 | 1-(2-Methoxy-phenyl)-3-(2-pyridin-3-yl-...)
Affinity DataKi:  1.00E+4nMAssay Description:Percent displacement of [3H]DPCPX binding in human adenosine A2B receptor expressed in COS-7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed