BDBM50323690 3-amino-4,6-dimethyl-N-(4-(trifluoromethyl)benzyl)thieno[2,3-b]pyridine-2-carboxamide::CHEMBL1212992::VU10008::cid_16757564

SMILES Cc1cc(C)c2c(N)c(sc2n1)C(=O)NCc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=WYOAEBODMMWELD-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50323690   

TargetMuscarinic acetylcholine receptor M4(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50323690(CHEMBL1212992 | VU10008 | cid_16757564 | 3-amino-4...)
Affinity DataEC50:  0.00242nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University Grant Title: Discovery of a Highly Selective in vitro and in vivo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2011
Entry Details
PCBioAssay
TargetMuscarinic acetylcholine receptor M4(Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50323690(CHEMBL1212992 | VU10008 | cid_16757564 | 3-amino-4...)
Affinity DataEC50:  715nMAssay Description:Allosteric activation of rat recombinant muscarinic M4 receptor expressed in CHO cells assessed as potentiation of 10 uM acetylcholine-induced calciu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed