BDBM50357219 CHEMBL1361446::US10800753, Compound (S)-vigabatrin::VIGABATRIN

SMILES N[C@H](CCC(O)=O)C=C

InChI Key InChIKey=PJDFLNIOAUIZSL-UHFFFAOYSA-N

Data  2 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50357219   

TargetProton-coupled amino acid transporter 1(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL

LigandBDBM50357219(CHEMBL1361446 | VIGABATRIN | US10800753, Compound ...)Copy SMILESCopy InChI

Affinity DataKi:  4.80E+6nMAssay Description:Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLKEGGPC cidPC sidSimilars

In Depth
Date in BDB:
7/21/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

Target4-aminobutyrate aminotransferase, mitochondrial(Human)
Northwestern University

US Patent

LigandBDBM50357219(CHEMBL1361446 | VIGABATRIN | US10800753, Compound ...)Copy SMILESCopy InChI

Affinity DataKi:  3.20E+6nMAssay Description:Inhibition constants were determined by monitoring GABA-AT activity in the presence of 0-50 mM concentrations of synthesized analogues using a couple...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLKEGGPC cidPC sidSimilars

In Depth
Date in BDB:
6/1/2021
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL