BDBM50461533 Emricasan::IDN-6556::PF-03491390::VAY-785::VAY785

SMILES C[C@H](NC(=O)C(=O)Nc1ccccc1C(C)(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)COc1c(F)c(F)cc(F)c1F

InChI Key InChIKey=SCVHJVCATBPIHN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50461533   

TargetCaspase-3(Human)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50461533(Emricasan | IDN-6556 | PF-03491390 | VAY-785 | VAY...)
Affinity DataIC50: 6nMAssay Description:Inhibition of Anti-Fas antibody-induced caspase-3 activity in human Jurkat E6-1 cells using Ac-DEVD-AMC substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed