BDBM86744 UR-AK62

SMILES NC(NC(=O)CC1CCCCC1)=NCCCc1cnc[nH]1

InChI Key InChIKey=GRHNPETZKNATKG-UHFFFAOYSA-N

Data  4 KI  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 86744   

TargetHistamine H1 receptor(Guinea pig)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM86744(UR-AK62)
Affinity DataKd:  2.45E+3nMAssay Description:Antagonist activity at histamine H1 receptor in guinea pig ileum assessed as inhibition of histamine-induced positive chronotropic activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetHistamine H2 receptor(Guinea pig)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM86744(UR-AK62)
Affinity DataEC50:  100nMAssay Description:Agonist activity at histamine H2 receptor in guinea pig spontaneously beating right atrium assessed as positive chronotropic activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetHistamine H2 receptor(Guinea pig)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM86744(UR-AK62)
Affinity DataKi:  23nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
University of Kansas

Curated by PDSP Ki Database
LigandPNGBDBM86744(UR-AK62)
Affinity DataKi:  62nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Guinea pig)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM86744(UR-AK62)
Affinity DataKi:  4.70E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
University of Kansas

Curated by PDSP Ki Database
LigandPNGBDBM86744(UR-AK62)
Affinity DataKi:  7.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed