BDBM50436201 FLUTRIMAZOLE::UR-4056

SMILES Fc1ccc(cc1)C(c1ccccc1)(c1ccccc1F)n1ccnc1

InChI Key InChIKey=QHMWCHQXCUNUAK-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50436201   

TargetNuclear receptor subfamily 1 group I member 2(Human)
City of Hope National Medical Center

Curated by ChEMBL
LigandPNGBDBM50436201(UR-4056 | FLUTRIMAZOLE)
Affinity DataEC50:  6.10E+3nMAssay Description:Agonist activity at PXR (unknown origin) expressed in human HepG2 cells assessed as induction of CYP3A4 transactivation after 16 hrs by luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBile acid receptor(Human)
City of Hope National Medical Center

Curated by ChEMBL
LigandPNGBDBM50436201(UR-4056 | FLUTRIMAZOLE)
Affinity DataIC50: 1.38E+4nMAssay Description:Antagonist activity at human GTS-tagged FXR after 20 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed