BDBM50105629 CHEMBL54893::N-(4-chloro-3-(3-methylbut-2-enyloxy)phenyl)-2-methylfuran-3-carbothioamide::N-{4-chloro-3-[(3-methylbut-2-enyl)oxy]phenyl}-2-methylfuran-3-carbothioamide::UC-781

SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#8]-c1cc(-[#7]-[#6](=S)-c2ccoc2-[#6])ccc1Cl

InChI Key InChIKey=JSNDJOKJRHLLQZ-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50105629   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50105629(UC-781 | N-{4-chloro-3-[(3-methylbut-2-enyl)oxy]ph...)
Affinity DataEC50:  9nMAssay Description:Effective concentration required against wild type HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50105629(UC-781 | N-{4-chloro-3-[(3-methylbut-2-enyl)oxy]ph...)
Affinity DataEC50:  24nMAssay Description:Effective concentration required against L100I mutant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50105629(UC-781 | N-{4-chloro-3-[(3-methylbut-2-enyl)oxy]ph...)
Affinity DataIC50: 226nMAssay Description:Inhibitory activity against E138K mutant reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50105629(UC-781 | N-{4-chloro-3-[(3-methylbut-2-enyl)oxy]ph...)
Affinity DataIC50: 23.8nMAssay Description:Inhibitory activity against wild-type HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50105629(UC-781 | N-{4-chloro-3-[(3-methylbut-2-enyl)oxy]ph...)
Affinity DataIC50: 20.8nMAssay Description:Inhibitory activity against R172A mutant reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed