BDBM50027056 (4,5-Dihydro-1H-imidazol-2-yl)-(5,6,7,8-tetrahydro-naphthalen-1-yl)-amine::CHEMBL32573::Imidazolidin-2-ylidene-(5,6,7,8-tetrahydro-naphthalen-1-yl)-amine::Tramazoline

SMILES [#6]-1-[#6]-[#7]\[#6](-[#7]-1)=[#7]\c1cccc2-[#6]-[#6]-[#6]-[#6]-c12

InChI Key InChIKey=NEEHDLNCAAFDSD-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50027056   

LigandPNGBDBM50027056(CHEMBL32573 | Tramazoline | Imidazolidin-2-ylidene...)
Affinity DataKi:  4.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2011
Entry Details
PubMed
LigandPNGBDBM50027056(CHEMBL32573 | Tramazoline | Imidazolidin-2-ylidene...)
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H]clonidine from Alpha-2 adrenergic receptor of rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2018
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Mouse)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50027056(CHEMBL32573 | Tramazoline | Imidazolidin-2-ylidene...)
Affinity DataKi:  15.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50027056(CHEMBL32573 | Tramazoline | Imidazolidin-2-ylidene...)
Affinity DataKi:  31.6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2012
Entry Details Article
PubMed
LigandPNGBDBM50027056(CHEMBL32573 | Tramazoline | Imidazolidin-2-ylidene...)
Affinity DataKi:  110nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2011
Entry Details
PubMed
TargetAlpha-2B adrenergic receptor(Human)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50027056(CHEMBL32573 | Tramazoline | Imidazolidin-2-ylidene...)
Affinity DataKi:  138nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2012
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Roche Bioscience

Curated by PDSP Ki Database
LigandPNGBDBM50027056(CHEMBL32573 | Tramazoline | Imidazolidin-2-ylidene...)
Affinity DataKi:  275nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2012
Entry Details Article
PubMed
LigandPNGBDBM50027056(CHEMBL32573 | Tramazoline | Imidazolidin-2-ylidene...)
Affinity DataKi:  290nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2011
Entry Details Article
PubMed