BDBM50646594 Dl-thiorphan::Thiorphan::NSC-727676

SMILES O=C(O)CNC(=O)C(CS)Cc1ccccc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50646594   

TargetNeprilysin(Human)
Birla Institute of Technology and Sciences Pilani

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646594BDBM50646594(Dl-thiorphan | Thiorphan | NSC-727676)
Affinity DataKi:  4nMAssay Description:Antagonist activity at human recombinant CL receptor /RAMP1 assessed as inhibition of cAMP accumulation by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
University of Naples Federico II

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646594BDBM50646594(Dl-thiorphan | Thiorphan | NSC-727676)
Affinity DataIC50: 1.80E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetPuromycin-sensitive aminopeptidase(Human)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646594BDBM50646594(Dl-thiorphan | Thiorphan | NSC-727676)
Affinity DataIC50: 5.73E+4nMAssay Description:Inhibition of human N-terminal His-tagged Puromycin-sensitive aminopeptidase extracted from Escherichia coli BL21 STAR (DE3) using alanine-4-methoxy-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAminopeptidase N(Human)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646594BDBM50646594(Dl-thiorphan | Thiorphan | NSC-727676)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Aminopeptidase N (unknown origin) using Ala-AMC as substrate incubated for 30 mins by SpectraMax microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed