BDBM50478728 CHEMBL490266::TX-2036

SMILES [#6]C([#6])([#6])c1ccc(-[#8]-[#6]-[#6@@H](-[#6]-n2ccnc2-[#7+](-[#8-])=O)-[#8]-[#6](=O)-c2ccc(-[#7]\[#6]=[#6]-3/[#6](=O)-[#6]=[#6]-[#6]-3=O)cc2)cc1

InChI Key InChIKey=GDQVOPZTIOGFAP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50478728   

Target72 kDa type IV collagenase(Human)
The University of Tokushima

Curated by ChEMBL
LigandPNGBDBM50478728(TX-2036 | CHEMBL490266)
Affinity DataIC50: 7.70E+4nMAssay Description:Inhibition of human bowes melanoma cell MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Bovine)
The University of Tokushima

Curated by ChEMBL
LigandPNGBDBM50478728(TX-2036 | CHEMBL490266)
Affinity DataIC50: 6.70E+4nMAssay Description:Inhibition of bovine arterial endothelial cell MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
The University of Tokushima

Curated by ChEMBL
LigandPNGBDBM50478728(TX-2036 | CHEMBL490266)
Affinity DataIC50: 1.84E+4nMAssay Description:Inhibition of Flt1 expressed in mouse NIH3T3 cells by autoradiographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
The University of Tokushima

Curated by ChEMBL
LigandPNGBDBM50478728(TX-2036 | CHEMBL490266)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human A431 cell EGFRK assessed as 32P phosphorylation by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed