BDBM50375667 CHEMBL437612::TX-1918

SMILES [#6]-c1cc(\[#6]=[#6]-2\[#6](=O)-[#6]=[#6]-[#6]-2=O)cc(-[#6])c1-[#8]

InChI Key InChIKey=POEHGBVHCSRUNJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50375667   

TargetEukaryotic elongation factor 2 kinase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50375667(TX-1918 | CHEMBL437612)
Affinity DataIC50: 440nMAssay Description:Inhibition of eEF2 kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50375667(TX-1918 | CHEMBL437612)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50375667(TX-1918 | CHEMBL437612)
Affinity DataIC50: 4.40E+5nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEukaryotic elongation factor 2 kinase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50375667(TX-1918 | CHEMBL437612)
Affinity DataIC50: 440nMAssay Description:Inhibition of eEF2K in human A431 cells using eEF2 as substrate preincubated for 30 mins followed by ATP/[gamma-32P]-ATP addition measured after 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2020
Entry Details Article
PubMed
TargetEukaryotic elongation factor 2 kinase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50375667(TX-1918 | CHEMBL437612)
Affinity DataIC50: 440nMAssay Description:Inhibition of eEF2K (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed