BDBM198120 TSA

SMILES CC(\C=C\C(=O)NO)\C=C(/C)C(=O)c1ccc(cc1)N(C)C

InChI Key InChIKey=ALCVRKZFLFWUAZ-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 198120   

TargetHistone deacetylase 6 [440-798](Zebrafish)
University of Pennsylvania

LigandPNGBDBM198120(TSA)
Affinity DataKi:  0.800nM ΔG°:  -12.4kcal/mole IC50: 1.40nMT: 2°CAssay Description:The fluorescence anisotropy assay was performed with fluorescein-labeled SAHA (fl-SAHA, gift of C. Fierke, University of Michigan) and measured using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6 [84-835](Human)
University of Pennsylvania

LigandPNGBDBM198120(TSA)
Affinity DataKi:  2.20nM ΔG°:  -11.8kcal/mole IC50: 3.90nMT: 2°CAssay Description:The fluorescence anisotropy assay was performed with fluorescein-labeled SAHA (fl-SAHA, gift of C. Fierke, University of Michigan) and measured using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetHistone deacetylase 6 [60-420](Zebrafish)
University of Pennsylvania

LigandPNGBDBM198120(TSA)
Affinity DataKi:  4.80nM ΔG°:  -11.3kcal/mole IC50: 7nMT: 2°CAssay Description:The fluorescence anisotropy assay was performed with fluorescein-labeled SAHA (fl-SAHA, gift of C. Fierke, University of Michigan) and measured using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed