BDBM50647810 TPX-0131::TPX0131::Tpx 0131::Tpx-0131::Zotizalkib

SMILES CC1(C)COc2ccc(F)cc2CN2c3nc4c(cnn4cc3OC[C@H]2C(F)F)C(=O)N1

InChI Key InChIKey=ILAMRXVQSGVCJX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50647810   

TargetALK tyrosine kinase receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50647810(Zotizalkib | Tpx 0131 | Tpx-0131 | TPX-0131 | TPX0...)
Affinity DataIC50: 1.40nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50647810(Zotizalkib | Tpx 0131 | Tpx-0131 | TPX-0131 | TPX0...)
Affinity DataIC50: 0.600nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed