BDBM50131440 10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulfinyl)-10H-phenothiazine::2-Methanesulfinyl-10-[2-(1-methyl-piperidin-2-yl)-ethyl]-10H-phenothiazine::CHEMBL1088::MESORIDAZINE::NC-123::Serentil::TPS-23

SMILES CN1CCCCC1CCN1c2ccccc2Sc2ccc(cc12)S(C)=O

InChI Key InChIKey=SLVMESMUVMCQIY-UHFFFAOYSA-N

Data  32 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 37 hits for monomerid = 50131440   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tcg Lifesciences

Curated by ChEMBL
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataIC50: 316nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tcg Lifesciences

Curated by ChEMBL
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataIC50: 324nMAssay Description:Inhibition of human ERG expressed in CHO cells by whole cell patch clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tcg Lifesciences

Curated by ChEMBL
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataIC50: 550nMAssay Description:Inhibitory concentration against potassium channel HERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tcg Lifesciences

Curated by ChEMBL
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataIC50: 320nMAssay Description:Inhibition of human ERG channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tcg Lifesciences

Curated by ChEMBL
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataIC50: 324nMAssay Description:Inhibition of human Potassium channel HERG expressed in mammalian cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataKi:  1.80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2011
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataKi:  1.81nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
In Depth
Date in BDB:
11/26/2011
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
In Depth
Date in BDB:
11/23/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Acadia Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataKi:  2.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Acadia Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataKi:  4.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataKi:  4.76nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
In Depth
Date in BDB:
2/20/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Stanford University

Curated by PDSP Ki Database
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataKi:  6.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Stanford University

Curated by PDSP Ki Database
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataKi:  6.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Stanford University

Curated by PDSP Ki Database
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataKi:  6.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed
TargetD(2) dopamine receptor(Rat)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataKi:  7.94nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
Acadia Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataKi:  9.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetD(4) dopamine receptor(Rat)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataKi:  13.4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataKi:  15nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Acadia Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataKi:  18.9nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Acadia Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataKi:  19nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2011
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataKi:  19nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataKi:  60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataKi:  69nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2011
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataKi:  71.4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataKi:  73nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Stanford University

Curated by PDSP Ki Database
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataKi:  79nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Stanford University

Curated by PDSP Ki Database
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataKi:  79.4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataKi:  90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataKi:  157nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2012
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataKi:  159nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Washington

Curated by PDSP Ki Database
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataKi:  380nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2012
Entry Details Article
PubMed
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataKi:  500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataKi:  1.60E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2011
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Mayo Clinic

Curated by PDSP Ki Database
LigandPNGBDBM50131440(CHEMBL1088 | 10-(2-(1-methylpiperidin-2-yl)ethyl)-...)
Affinity DataKi:  1.61E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details Article
PubMed