BDBM214777 TLM18

SMILES C/C(=C\[C@@]1(C(=C(C(=O)S1)CCCCN=[N+]=[N-])O)C)/C=C

InChI Key InChIKey=YWCFDTCBMVZYIG-UHFFFAOYSA-N

Data  1 KI  3 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 214777   

Target3-oxoacyl-[acyl-carrier-protein] synthase 1(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Wuerzburg

LigandPNGBDBM214777(TLM18)
Affinity DataKd:  1.12E+5nMpH: 8.5Assay Description:Binding of TLM18 to wild-type and mutant KasA was quantified by monitoring changes in the intrinsic tryptophan fluorescence of the enzyme at waveleng...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target3-oxoacyl-[acyl-carrier-protein] synthase 2(Staphylococcus aureus)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM214777(TLM18)
Affinity DataKd:  1.07E+5nMAssay Description:Binding affinity to Staphylococcus aureus wild type FabF expressed in Escherichia coli BL21 (DE3) PlysS cells by intrinsic tryptophan fluorescence qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 2(Staphylococcus aureus)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM214777(TLM18)
Affinity DataKd:  1.07E+5nMAssay Description:Binding affinity to Staphylococcus aureus wild type FabF expressed in Escherichia coli BL21 (DE3) PlysS cells by intrinsic tryptophan fluorescence qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 1 [C171Q](Mycobacterium tuberculosis)
University of Wuerzburg

LigandPNGBDBM214777(TLM18)
Affinity DataKi:  3.84E+5nMpH: 8.5Assay Description:Binding of TLM18 to wild-type and mutant KasA was quantified by monitoring changes in the intrinsic tryptophan fluorescence of the enzyme at waveleng...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)