BDBM50092613 Salvigenin

SMILES COc1ccc(cc1)-c1cc(=O)c2c(O)c(OC)c(OC)cc2o1

InChI Key InChIKey=QCDYOIZVELGOLZ-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50092613   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
The Chinese University of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM50092613(Salvigenin)
Affinity DataIC50: 580nMAssay Description:Inhibition of recombinant N-terminal GST/His6-tagged human FLT3 ITD mutant (571 to 993 residues) expressed in Sf9 insect cells incubated for 1 hr by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
The Chinese University of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM50092613(Salvigenin)
Affinity DataIC50: 290nMAssay Description:Inhibition of recombinant His-tagged human FLT3 D835Y mutant (564 to 958 residues) expressed in baculovirus expression system using tyr 02 as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
The Chinese University of Hong Kong (Shenzhen)

Curated by ChEMBL
LigandPNGBDBM50092613(Salvigenin)
Affinity DataIC50: 550nMAssay Description:Inhibition of recombinant His-tagged human FLT3 (564 to 958 residues) expressed in baculovirus expression system using tyr 02 as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50092613(Salvigenin)
Affinity DataKi: >2.60E+4nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor (unknown origin) transfected into HEK293 cells by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed