BDBM50071112 CHEMBL56835::N-[4-(4-Acetylamino-4-phenyl-piperidin-1-yl)-2-(3,4-dichloro-phenyl)-butyl]-N-methyl-benzamide::SR 48968

SMILES CN(CC(CCN1CCC(CC1)(NC(C)=O)c1ccccc1)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1

InChI Key InChIKey=PGKXDIMONUAMFR-UHFFFAOYSA-N

Data  15 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50071112   

TargetSubstance-K receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50071112(SR 48968 | CHEMBL56835 | N-[4-(4-Acetylamino-4-phe...)
Affinity DataIC50: 8.90nMAssay Description:Binding affinity towards human Tachykinin receptor 2 using [125I]- NKA radioligand expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50071112(SR 48968 | CHEMBL56835 | N-[4-(4-Acetylamino-4-phe...)
Affinity DataKi:  0.230nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2012
Entry Details
PubMed
TargetSubstance-K receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50071112(SR 48968 | CHEMBL56835 | N-[4-(4-Acetylamino-4-phe...)
Affinity DataKi:  0.400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2012
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50071112(SR 48968 | CHEMBL56835 | N-[4-(4-Acetylamino-4-phe...)
Affinity DataKi:  0.440nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details
PubMed
TargetSubstance-K receptor(Bovine)
Hoechst Marion Roussel

Curated by PDSP Ki Database
LigandPNGBDBM50071112(SR 48968 | CHEMBL56835 | N-[4-(4-Acetylamino-4-phe...)
Affinity DataKi:  0.710nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details
PubMed
TargetSubstance-K receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50071112(SR 48968 | CHEMBL56835 | N-[4-(4-Acetylamino-4-phe...)
Affinity DataKi:  1.75nMAssay Description:Displacement of [3H]- NKA from human NK-2 receptor expressed in MEL cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50071112(SR 48968 | CHEMBL56835 | N-[4-(4-Acetylamino-4-phe...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]- NKA from human NK-2 receptor expressed in MEL cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Golden hamster)
Hoechst Marion Roussel

Curated by PDSP Ki Database
LigandPNGBDBM50071112(SR 48968 | CHEMBL56835 | N-[4-(4-Acetylamino-4-phe...)
Affinity DataKi:  7.32nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details
PubMed
TargetNeuromedin-K receptor(Guinea pig)
Hoechst Marion Roussel

Curated by PDSP Ki Database
LigandPNGBDBM50071112(SR 48968 | CHEMBL56835 | N-[4-(4-Acetylamino-4-phe...)
Affinity DataKi:  208nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details
PubMed
TargetSubstance-P receptor(Guinea pig)
Hoechst Marion Roussel

Curated by PDSP Ki Database
LigandPNGBDBM50071112(SR 48968 | CHEMBL56835 | N-[4-(4-Acetylamino-4-phe...)
Affinity DataKi:  217nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details
PubMed
TargetSubstance-P receptor(Human)
Schering-Plough Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50071112(SR 48968 | CHEMBL56835 | N-[4-(4-Acetylamino-4-phe...)
Affinity DataKi:  273nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2012
Entry Details Article
PubMed
TargetNeuromedin-K receptor(Human)
Sanofi Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50071112(SR 48968 | CHEMBL56835 | N-[4-(4-Acetylamino-4-phe...)
Affinity DataKi:  368nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2011
Entry Details
PubMed
TargetSubstance-P receptor(Human)
Schering-Plough Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50071112(SR 48968 | CHEMBL56835 | N-[4-(4-Acetylamino-4-phe...)
Affinity DataKi:  454nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2012
Entry Details
PubMed
TargetSubstance-P receptor(Human)
Schering-Plough Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50071112(SR 48968 | CHEMBL56835 | N-[4-(4-Acetylamino-4-phe...)
Affinity DataKi:  593nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details
PubMed
TargetNeuromedin-K receptor(Human)
Sanofi Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50071112(SR 48968 | CHEMBL56835 | N-[4-(4-Acetylamino-4-phe...)
Affinity DataKi:  707nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2012
Entry Details
PubMed
TargetNeuromedin-K receptor(Human)
Sanofi Recherche

Curated by PDSP Ki Database
LigandPNGBDBM50071112(SR 48968 | CHEMBL56835 | N-[4-(4-Acetylamino-4-phe...)
Affinity DataKi:  1.28E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2012
Entry Details Article
PubMed