BDBM103832 SPI-07::US11041859, Code SPI-07

SMILES Cc1cc(N)ccc1\N=N\c1cc(c2cccc(c2c1)S([O-])(=O)=O)S([O-])(=O)=O

InChI Key InChIKey=XXZDPVOWJBCNQC-UHFFFAOYSA-L

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 103832   

TargetSentrin-specific protease 1(Human)
Beckman Research Institute of The City of Hope

LigandPNGBDBM103832(SPI-07 | US11041859, Code SPI-07)
Affinity DataIC50: 6.00E+7nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2014
Entry Details Article
PubMed
TargetSentrin-specific protease 2(Human)
Beckman Research Institute of The City of Hope

LigandPNGBDBM103832(SPI-07 | US11041859, Code SPI-07)
Affinity DataIC50: 6.00E+4nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2014
Entry Details Article
PubMed
TargetSentrin-specific protease 1(Human)
Beckman Research Institute of The City of Hope

LigandPNGBDBM103832(SPI-07 | US11041859, Code SPI-07)
Affinity DataIC50: 1.75E+4nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2014
Entry Details Article
PubMed
TargetSentrin-specific protease 2(Human)
Beckman Research Institute of The City of Hope

LigandPNGBDBM103832(SPI-07 | US11041859, Code SPI-07)
Affinity DataIC50: 2.81E+4nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2014
Entry Details Article
PubMed
LigandPNGBDBM103832(SPI-07 | US11041859, Code SPI-07)
Affinity DataIC50: 6.00E+4nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2021
Entry Details
Go to US Patent

LigandPNGBDBM103832(SPI-07 | US11041859, Code SPI-07)
Affinity DataIC50: 6.00E+4nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2021
Entry Details
Go to US Patent

TargetSmall ubiquitin-related modifier 1/2(Human)
City of Hope

US Patent
LigandPNGBDBM103832(SPI-07 | US11041859, Code SPI-07)
Affinity DataIC50: 1.75E+4nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2021
Entry Details
Go to US Patent

LigandPNGBDBM103832(SPI-07 | US11041859, Code SPI-07)
Affinity DataIC50: 2.81E+4nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2021
Entry Details
Go to US Patent

TargetSentrin-specific protease 1(Human)
Beckman Research Institute of The City of Hope

LigandPNGBDBM103832(SPI-07 | US11041859, Code SPI-07)
Affinity DataIC50: 6.00E+4nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2021
Entry Details
Go to US Patent

TargetSentrin-specific protease 2(Human)
Beckman Research Institute of The City of Hope

LigandPNGBDBM103832(SPI-07 | US11041859, Code SPI-07)
Affinity DataIC50: 6.00E+4nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2021
Entry Details
Go to US Patent

TargetSentrin-specific protease 7(Human)
City of Hope

US Patent
LigandPNGBDBM103832(SPI-07 | US11041859, Code SPI-07)
Affinity DataIC50: 1.90E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2021
Entry Details
Go to US Patent