BDBM50138983 (S)-2-Amino-5-(2-methyl-isothioureido)-pentanoic acid::2-(S)-Amino-5-(2-methyl-isothioureido)-pentanoic acid::2-Amino-5-(2-methyl-isothioureido)-pentanoic acid::CHEMBL106516::N~5~-[(E)-imino(methylsulfanyl)methyl]-L-ornithine::S-methyl-L-thiocitrulline::SMTC, 5

SMILES CSC(N)=NCCC[C@H](N)C(O)=O

InChI Key InChIKey=NGVMVBQRKZPFLB-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50138983   

TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
The University of Texas

LigandPNGBDBM50138983(2-(S)-Amino-5-(2-methyl-isothioureido)-pentanoic a...)
Affinity DataAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50138983(2-(S)-Amino-5-(2-methyl-isothioureido)-pentanoic a...)
Affinity DataIC50: 300nMAssay Description:Inhibitory concentration against human inducible nitric oxide synthase expressed in Sf-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50138983(2-(S)-Amino-5-(2-methyl-isothioureido)-pentanoic a...)
Affinity DataIC50: 400nMAssay Description:Inhibitory concentration against human endothelial nitric oxide synthase expressed in Sf-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50138983(2-(S)-Amino-5-(2-methyl-isothioureido)-pentanoic a...)
Affinity DataIC50: 60nMAssay Description:Inhibitory concentration against human neuronal nitric oxide synthase expressed in Sf-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50138983(2-(S)-Amino-5-(2-methyl-isothioureido)-pentanoic a...)
Affinity DataIC50: 60nMAssay Description:Inhibitory activity against neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50138983(2-(S)-Amino-5-(2-methyl-isothioureido)-pentanoic a...)
Affinity DataKi:  50nMAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2013
Entry Details Article
PubMed